ABSTRACT Introduction and objectives: The safety of physiology-based revascularization in patients with diabetes mellitus has been scarcely investigated.Our objective was to determine the safety of deferring revascularization based on the fractional flow reserve (FFR) or the instantaneous wave-free ratio (iFR) in diabetic patients.Methods: Single-c
Deciphering the Mechanism of Bushen Huoxue Decotion on Decidualization by Intervening Autophagy via AMPK/mTOR/ULK1: A Novel Discovery for URSA Treatment
Impaired decidualization was recognized as one of the crucial pathomechanisms accounting for unexplained recurrent spontaneous abortion (URSA).Currently, the exact molecular mechanism and targeted clinical decision are still in exploration.Bushen Huoxue decoction (BSHXD) has previously been proved effective in treating URSA, but its mechanism remai
Effects of Trace Erbium Addition on Microstructure and Mechanical Properties of Ti6Al4V-xEr Alloys
In order to discern the effect of rare earth PEACH element Er addition on grain refinement of the most widely used titanium alloy Ti6Al4V, new erbium modified Ti6Al4V alloys with compositions of Ti6Al4V-xEr (x = 0, 0.2, 0.4, 0.6 wt %) were developed and investigated for their microstructural characteristics and mechanical properties in comparison w
Large-eddy simulations of surface roughness parameter sensitivity to canopy-structure characteristics
Surface roughness parameters, namely the roughness length and displacement height, are an integral input used to model surface fluxes.However, most models assume these parameters to be a fixed property of plant functional type and disregard the governing structural heterogeneity and dynamics.In this study, we use large-eddy simulations to explore,